1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-130752
    VNI
    Inhibitor
    VNI is an effective inhibitor of CYP51. VNI can inhibit sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.
    VNI
  • HY-B1344R
    Oxantel pamoate (Standard)
    Inhibitor
    Oxantel pamoate (Standard) (Oxantel embonate (Standard)) is the analytical standard of Oxantel pamoate (HY-B1344). This product is intended for research and analytical applications. Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM).
    Oxantel pamoate (Standard)
  • HY-134220
    Doramectin monosaccharide
    Doramectin monosaccharide is an acid degradation product of Doramectin (HY-17035), a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
    Doramectin monosaccharide
  • HY-13735AR
    Quinacrine dihydrochloride (Standard)
    Inhibitor
    Quinacrine (dihydrochloride) (Standard) is the analytical standard of Quinacrine (dihydrochloride). This product is intended for research and analytical applications. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis.
    Quinacrine dihydrochloride (Standard)
  • HY-W774926
    Permethrin-d6
    Inhibitor
    Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes).
    Permethrin-d<sub>6</sub>
  • HY-N7236
    Pervicoside B
    Inhibitor
    Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases.
    Pervicoside B
  • HY-135625
    BPH-1218
    BPH-1218 is an inhibitor of squalene synthase (SQS), with the IC50 of 31 nM and 64 nM for TcSQS and HsSQS, respectively, that can be used as an anti-infective agent.
    BPH-1218
  • HY-173051
    Antiparasitic agent-24
    Inhibitor
    Antiparasitic agent-24 (Compound 14a) is an antiparasitic agent, with EC50s of 0.005 μM (L. maj), 0.069 μM (L. don), 0.82 μM (T. brucei), 4.1 μM (T. cruzi) respectively.
    Antiparasitic agent-24
  • HY-15311R
    Avermectin B1 (Standard)
    Inhibitor
    Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy.
    Avermectin B1 (Standard)
  • HY-126660
    Cinerubin A
    Inhibitor
    Cinerubin A (Cinerubine A) has anti-Gram-positive bacteria, mycobacterium, fungis and amoeba activity, and has strong effect on mouse adenocarcinoma E0771.
    Cinerubin A
  • HY-121768
    Trimethacarb
    Trimethacarb is a type of insecticide used for pest control.
    Trimethacarb
  • HY-B2157R
    Robenidine hydrochloride (Standard)
    Inhibitor
    Robenidine hydrochloride (Standard) is the analytical standard of Robenidine hydrochloride. This product is intended for research and analytical applications. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.
    Robenidine hydrochloride (Standard)
  • HY-W011517R
    2-Fluoroadenosine (Standard)
    Inhibitor
    2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions.
    2-Fluoroadenosine (Standard)
  • HY-N15095
    Aplasmomycin
    Inhibitor
    Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo.
    Aplasmomycin
  • HY-B1896AR
    Piperaquine phosphate (Standard)
    Inhibitor
    Piperaquine (phosphate) (Standard) is the analytical standard of Piperaquine (phosphate). This product is intended for research and analytical applications. Piperaquine phosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin.
    Piperaquine phosphate (Standard)
  • HY-76204S
    Glycine ethyl ester-13C hydrochloride
    Inhibitor
    Glycine ethyl ester-13C hydrochloride is a 13C-labeled Glycine ethyl ester hydrochloride (HY-76204). Glycine ethyl ester monohydrochloride is a Glycine (HY-Y0966) derivative.
    Glycine ethyl ester-<sup>13</sup>C hydrochloride
  • HY-N2932
    β-Yohimbine
    Inhibitor
    β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL).
    β-Yohimbine
  • HY-112785
    Pyriftalid
    Pyriftalid is a new type of insecticide with strong inhibitory activity against a variety of pests. Pyriftalid is widely used in agriculture to effectively control pests on crops, thereby improving crop yield and quality. Pyriftalid is also being studied for improving plant resistance to resist attacks by pests and diseases.
    Pyriftalid
  • HY-B1881S
    Pirimiphos-methyl-d6
    Inhibitor
    Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl (HY-B1881). Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
    Pirimiphos-methyl-d<sub>6</sub>
  • HY-136394R
    Diafenthiuron (Standard)
    Inhibitor
    Diafenthiuron (Standard) is the analytical standard of Diafenthiuron. This product is intended for research and analytical applications. Diafenthiuron is a thiourea compound commonly used pesticide. Diafenthiuron inhibits mitochondrial functioning in insect pests.
    Diafenthiuron (Standard)

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