1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-136458R
    3-ANOT (Standard)
    Inhibitor
    3-ANOT (Standard) is the analytical standard of 3-ANOT. This product is intended for research and analytical applications. 3-ANOT is a metabolite of Dinitolmide (a nitroamide coccidiostat commonly used in poultry production).
    3-ANOT (Standard)
  • HY-123192
    Uredofos
    Inhibitor
    Uredofos is a broad-spectrum anthelmintic. Uredofos has anticestodal activity.
    Uredofos
  • HY-151217R
    Ipronidazole (Standard)
    Inhibitor
    Ipronidazole (Standard) is the analytical standard of Ipronidazole. This product is intended for research and analytical applications. Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water.
    Ipronidazole (Standard)
  • HY-100586R
    Ibuprofen L-lysine (Standard)
    Ibuprofen (L-lysine) (Standard) is the analytical standard of Ibuprofen (L-lysine). This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) L-lysine is a potent orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen L-lysine inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen L-lysine is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen L-lysine can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen L-lysine (Standard)
  • HY-B0537A
    Pentamidine dihydrochloride
    Inhibitor
    Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
    Pentamidine dihydrochloride
  • HY-W016621
    3,4-Methylenedioxypropiophenone
    Inhibitor 98.13%
    3,4-Methylenedioxypropiophenone (Compound 4) is an isomer of 3,4-methylenedioxyphenyl-2-propanone. 3,4-Methylenedioxypropiophenone has potent activity against leishmania.
    3,4-Methylenedioxypropiophenone
  • HY-W040073R
    Nifurtimox (Standard)
    Inhibitor
    Nifurtimox (Standard) is the analytical standard of Nifurtimox. This product is intended for research and analytical applications. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).
    Nifurtimox (Standard)
  • HY-W197328
    Isonicotinaldehyde 2-pyridin
    Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action.
    Isonicotinaldehyde 2-pyridin
  • HY-137229
    Avermectin B1a monosaccharide
    Inhibitor
    Avermectin B1a monosaccharide is a macrolide anthelmintic that can inhibit Caenorhabditis elegans.
    Avermectin B1a monosaccharide
  • HY-169510
    Aurachin C
    Inhibitor
    Aurachin C is an isoprenoid quinoline alkaloid with antiplasmodial, antifungal and antibacterial effects. Aurachin C is a selective terminal oxidases inhibitor.
    Aurachin C
  • HY-170768
    Alkaline tryptase-IN-1
    Inhibitor
    Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline tryptase. The LC50 of Alkaline tryptase-IN-1 inhibits Aphid graminearum, Schizaphis graminearum, Aphid natans, Aphid oleraceus, Aphid fusca, Aphid mariana, and Myzus persicae with concentrations of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL, respectively.
    Alkaline tryptase-IN-1
  • HY-B0937AR
    Amprolium (hydrochloride) (Standard)
    Inhibitor
    Amprolium (hydrochloride) (Standard) is the analytical standard of Amprolium (hydrochloride). This product is intended for research and analytical applications. Amprolium hydrochloride is an anticoccidial drug used in poultry. It is a thiamine-like substance that inhibits thiamine transport in coccidia by inhibiting thiamine absorption and carbohydrate synthesis.
    Amprolium (hydrochloride) (Standard)
  • HY-129228
    Lychnopholide
    Inhibitor
    Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models.
    Lychnopholide
  • HY-122274
    MMV666693
    MMV666693 is a translation inhibitor specific for Plasmodium falciparum. MMV666693 has low cytotoxicity in human fibroblasts (IC50>32 µM) and can be used in the development of antimalarial drugs.
    MMV666693
  • HY-N14239
    Jietacin A
    Inhibitor
    Jietacin A is found to be resistant to nematode, it can kill Burs helenchus Lignicolus with the concentration of 0.25 μg/mL.
    Jietacin A
  • HY-N2392R
    Kukoamine A (Standard)
    Inhibitor
    Kukoamine A (Standard) is the analytical standard of Kukoamine A. This product is intended for research and analytical applications. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity.
    Kukoamine A (Standard)
  • HY-N0565S3
    Doxycycline-13C,d3
    Doxycycline-13C,d3 is 13C and deuterium labeled Doxycycline. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity.
    Doxycycline-<sup>13</sup>C,d<sub>3</sub>
  • HY-15308R
    Avermectin B1a (Standard)
    Inhibitor
    Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a (Standard)
  • HY-114763
    LP8
    Inhibitor
    LP8 is a Pyridinyl-type CYP51 inhibitor and can be used for study of chagas disease and American trypanosomiasis.
    LP8
  • HY-159963
    PfCLK3-IN-1
    Inhibitor
    PfCLK3-IN-1 (Compound 4) is a covalent inhibitor for Plasmodium falciparum CLK3 (Pf CLK3) under alkaline conditions with an pEC50 of 7.1. PfCLK3-IN-1 reduces mature gametocytes in sexual stage parasites, and prevents transmission. PfCLK3-IN-1 inhibits P. falciparum Dd2-B2 clone with an IC50 of 239.5 nM.
    PfCLK3-IN-1

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